ABC294640 from CAYMAN CHEMICAL COMPANY
Search, find, compare suppliers for ABC294640 products.
| Edit | |
|---|---|
| Product Name | ABC294640 |
| Description | An inhibitor of SPHK2 (Ki = 9.8 µM); inhibits SPHK2 (IC50 = 60 µM) without affecting SPHK1 activity up to 100 µM but does reduce SPHK1a protein levels in cells via an SPHK1-indirect proteasomal-dependent mechanism at 5-25 µM; inactive against a panel of 20 lipid-regulated kinases at 50 µM; inhibits proliferation of a variety of human cancer cell lines (IC50s = 6, 12.2, 32.8, and 48.1 µM, respectively); reduces tumor growth in a mouse syngeneic model of mammary adenocarcinoma at 35 and 100 mg/kg every other day; reduces colonic inflammation in mouse and rat models of Crohn's disease |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | ABC-294640 SPHK-2 1 1a MDAMB231 HT29 A498 opaganib 3H-S1P IBD LNCapAI Hep G2 PANC1 |
| Gene, Accession, CAS # | CAS: 915385-81-8 |
| Catalog # | 10587-10 |
| Price | $235.00 |
| Order / More Info | ABC294640 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY