Malabaricone B from CAYMAN CHEMICAL COMPANY
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| Product Name | Malabaricone B |
| Description | A diarylnonanoid with diverse biological activities; an inhibitor of sphingomyelin synthase 1 and -2 (IC50s = 3.5 and 2.5 µM, respectively); active against S. aureus, B. subtilis, and S. durans (MIC = 1 µg/ml for all) and three strains of C. albicans (MICs = 4-16 µg/ml); cytotoxic to A549, A375, Jurkat, A431, U937, and MCF-7 cells (IC50s = 8.1, 26.7, 27.4, 9.5, 27.5, and 9.3 µM, respectively) but not non-cancerous cells; increases the levels of ROS and induces apoptosis in A549 cells; reduces TBARS formation by 28.2% in rat liver mitochondria at 2 µg/ml; reduces stomach ulceration in a mouse model of indomethacin-induced gastric ulcer at 10, 15, and 20 mg/kg |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | NSC 287967|NSC 630196 |
| Gene, Accession, CAS # | CAS: 63335-24-0 |
| Catalog # | 29911-10 |
| Price | $275.00 |
| Order / More Info | Malabaricone B from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY