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Product Name | Zafirlukast |
Description | A CysLT1 receptor antagonist (IC50 = 0.014 µM in a cell-based calcium mobilization assay); selective for CysLT1 over CysLT2 receptors (IC50 = 58 µM); inhibits LTD4-induced mucus secretion in isolated guinea pig trachea (IC50 = 0.6 µM); inhibits ovalbumin-induced increases in tracheal mucus secretion in ovalbumin-sensitized guinea pigs by 65% at 5 µM; inhibits LTD4-induced bronchoconstriction in anesthetized guinea pigs (ED50 = 61 nmol/kg, i.v.) |
Size | 500 mg |
Concentration | n/a |
Applications | n/a |
Other Names | cysteinyl-leukotrienes cysLT1 receptors GPCRs protein-coupled antagonists asthma asthmatic allergies allergic rhinitis selective cysLTs cys-LTs cys-LT1 accolate™ |
Gene, Accession, CAS # | CAS: 107753-78-6 |
Catalog # | 10008282-500 |
Price | $595.00 |
Order / More Info | Zafirlukast from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |