Edicotinib from CAYMAN CHEMICAL COMPANY
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| Product Name | Edicotinib |
| Description | A CSF1R inhibitor (IC50 = 3.2 nM); selective for CSF1R over KIT and FLT3 (IC50s = 20 and 190 nM, respectively); reduces CSF1-induced phosphorylation of CSF1R and ERK1/2 in N13 microglia at 0.1-1,000 nM; reduces spinal motor neuron degeneration and increases the latency to fall in the rotarod test in the P301S mouse model of tauopathy; reduces increases in the colonic weight to length ratio, as well as decreases colonic infiltration of macrophages, neutrophils, and CD3+ T cells, in an adoptive T cell transfer-induced mouse model of colitis at 15 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | JNJ-40346527|JNJ-527 |
| Gene, Accession, CAS # | CAS: 1142363-52-7 |
| Catalog # | 33347-5 |
| Price | $216.00 |
| Order / More Info | Edicotinib from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY