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Product Name | Urapidil (hydrochloride) |
Description | An α1-AR antagonist and partial 5-HT1A agonist; selectively binds to α1- over α2-ARs (IC50s = 0.74 and 42 µM, respectively) and to 5-HT1A over 5-HT1B and 5-HT2 receptors (IC50s = 0.4, 20.4, and >10 µM, respectively) in rat cortex; inhibits forskolin-induced cAMP accumulation in calf hippocampus as a functional model for 5-HT1A receptors (EC50 = 390 nM); inhibits the isoproterenol-induced positive chronotroptic response in isolated rat atria (pA2 = 6.05); lowers MAP in anesthetized cats at 1 µmol/kg, i.v. |
Size | 250 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 34661-75-1 α-1 α1AR 5HT 1-A 1-B HT-1A HT-2 α-2 α2AR β-1 β1AR pA-2 |
Gene, Accession, CAS # | CAS: 64887-14-5 |
Catalog # | 29004-250 |
Price | $73.00 |
Order / More Info | Urapidil (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |