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Product Name | TLR7 Agonist 2 |
Description | A TLR7 agonist (LEC = 0.4 µM in a cell-based reporter assay); selective for TLR7 over TLR8 (LEC = >100 µM); increases IFN-α levels and the ISG response, increasing the expression of Oas1b, Isg15, and Mx1, in mouse liver and plasma at 0.3-10 mg/kg; increases plasma levels of IFN-α, CCL2, IL-6, IL-1Ra, G-CSF, and IL-10 in cynomolgus monkeys at 10 mg/kg; reduces serum and liver viral load in the HDI-HBV mouse model at 0.3-5 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Toll-Like Receptor 7 Agonist 2 |
Gene, Accession, CAS # | CAS: 1642857-69-9 |
Catalog # | 28450-1 |
Price | $121.00 |
Order / More Info | TLR7 Agonist 2 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |