TLR7 Agonist 2 from CAYMAN CHEMICAL COMPANY

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Product NameTLR7 Agonist 2
DescriptionA TLR7 agonist (LEC = 0.4 µM in a cell-based reporter assay); selective for TLR7 over TLR8 (LEC = >100 µM); increases IFN-α levels and the ISG response, increasing the expression of Oas1b, Isg15, and Mx1, in mouse liver and plasma at 0.3-10 mg/kg; increases plasma levels of IFN-α, CCL2, IL-6, IL-1Ra, G-CSF, and IL-10 in cynomolgus monkeys at 10 mg/kg; reduces serum and liver viral load in the HDI-HBV mouse model at 0.3-5 mg/kg
Size1 mg
Concentrationn/a
Applicationsn/a
Other NamesToll-Like Receptor 7 Agonist 2
Gene, Accession, CAS #CAS: 1642857-69-9
Catalog #28450-1
Price$121.00
Order / More InfoTLR7 Agonist 2 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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