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Product Name | MK-7655 |
Description | A β-lactamase inhibitor; inhibits hydrolysis of nitrocefin by KPC-2 β-lactamase from K. pneumoniae and AmpC β-lactamase from P. aeruginosa (IC50s = 210 and 465 nM, respectively); restores imipenem sensitivity to resistant clinical isolates of P. aeruginosa and K. pneumoniae (MIC50s = 0.25-2 and 8-16 µM in the presence and absence of MK-7655, respectively); produces a bacteriostatic effect in mouse thigh models of K. pneumoniae and P. aeruginosa infection when administered with imipenem and cilastatin (48.9 mg/kg per day) |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Relebactam Klebsiella Pseudomonas Acinetobacter MK7655 |
Gene, Accession, CAS # | CAS: 1174018-99-5 |
Catalog # | 23890-25 |
Price | $704.00 |
Order / More Info | MK-7655 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |