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Product Name | Treprostinil (diethanolamine salt) |
Description | An agonist of IP2, DP2, and EP2 receptors; binds selectively to IP2, DP2, and EP2 over EP1, EP3, and EP4 receptors (Kis = 32, 4.4, 3.6, 212, 2,505, and 826 nM, respectively, in radioligand binding assays); inhibits LPS-induced production of TNF-α, IL-1β, IL-6, and GM-CSF in in isolated human alveolar macrophages at 200 ng/ml; relaxes isolated small pulmonary arteries and veins precontracted with U-46619; reduces right ventricular systolic pressure compared to hypoxic and sham control animals in a mouse model of chronic hypoxic pulmonary hypertension |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Treprostinil diolamine|UT 15C |
Gene, Accession, CAS # | CAS: 830354-48-8 |
Catalog # | 11927-5 |
Price | $477.00 |
Order / More Info | Treprostinil (diethanolamine salt) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |