Dehydroandrographolide from CAYMAN CHEMICAL COMPANY
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| Product Name | Dehydroandrographolide |
| Description | A diterpene with diverse biological activities; inhibits DNA replication of HBV in HepG2 2.2.15 cells (IC50 = 22.6 µM); inhibits ANO1 chloride currents in Fisher rat thyroid cells expressing human ANO1 and SW620 cells at 50 µM; inhibits the proliferation of SW620 cells; reduces the release of histamine, tryptase beta, β-hexosaminidase, TNF-α, and CCL2, as well as inhibits SP-induced cellular degranulation in LAD 2 and mouse primary mast cells; upregulates phosphorylation of SHP-1 and SHP-2 in LAD 2 cells with CD300f knocked down using siRNA at 50 µM; inhibits SP-induced mast cell degranulation and reduces mouse serum levels of histamine, tryptase beta 2, TNF-α, CCL2, and CXCL2 in vivo at 1 or 2 mg/kg |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | dehydro-andrographolide Andrographis ANO 1 TMEM 16A SW 620 TNFα CC CCL CXCL CXC 2 LAD2 SHP1 SHP2 |
| Gene, Accession, CAS # | CAS: 134418-28-3 |
| Catalog # | 31625-25 |
| Price | $168.00 |
| Order / More Info | Dehydroandrographolide from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY