Carbamazepine from CAYMAN CHEMICAL COMPANY
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| Product Name | Carbamazepine |
| Description | A sodium channel inhibitor; preferentially inhibits inactivated Nav1.7 and Nav1.3 channels (IC50s = 406 and 900 µM, respectively) over resting (closed) Nav1.7 and Nav1.3 channels in whole-cell patch-clamp assays using HEK293 cells (IC50s = 1,584 and 2,464 µM, respectively); inhibits sodium currents in a rat sciatic nerve patch-clamp assay ex vivo at 100 µM; reduces dopamine levels in the striatum and hippocampus, as well as L-DOPA levels in the striatum, in rats at 100 mg/kg; reduces amphetamine-induced hyperactivity in mice at 0.5% w/w in the diet; reduces immobility time in the forced swim test in mice at 0.75% w/w in the diet |
| Size | 5 g |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CBZ|NSC 169864 |
| Gene, Accession, CAS # | CAS: 298-46-4 |
| Catalog # | 15422-5 |
| Price | $26.00 |
| Order / More Info | Carbamazepine from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY