2,5-dimethyl Celecoxib from CAYMAN CHEMICAL COMPANY

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Product Name2,5-dimethyl Celecoxib
DescriptionAn anticancer celecoxib derivative; does not inhibit COX-2 (IC50 = >100 µM); inhibits mPGES-1 in HeLa cells (IC50 = 15.6 µM); reduces PGE2 production in HeLa, A549, and HCA-7 cells (IC50s = 0.64, 0.83, and 3.08 µM, respectively); inhibits proliferation of drug-sensitive RPMI8226 and multidrug-resistant 8226/Dox40 multiple myeloma cells; increases the rate of apoptosis in RPMI8226 and 8226/Dox40 cells at 20 and 30 µM; the antiproliferative effect of 2,5-dimethyl celecoxib is independent of mPGES-1 inhibition
Size10 mg
Concentrationn/a
Applicationsn/a
Other NamesDMC
Gene, Accession, CAS #CAS: 457639-26-8
Catalog #10008006-10
Price$92.00
Order / More Info2,5-dimethyl Celecoxib from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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