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Product Name | Nicorandil |
Description | A SUR2B/Kir6.2 activator (EC50 = ~10 µM) and nitric oxide donor; selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 µM); activates soluble guanylate cyclase in a cell-free assay and relaxes partially depolarized isolated bovine coronary artery strips (EC50 = 4.4 µM); decreases mean blood pressure, coronary resistance, and heart rate, as well as increases coronary sinus outflow, in dogs at 1 mg/kg i.v.; increases survival and decreases infarct size in a rabbit model of left coronary artery occlusion-induced myocardial ischemia-reperfusion injury |
Size | 250 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-Nicotinamidoethyl nitrate|SG-75 |
Gene, Accession, CAS # | CAS: 65141-46-0 |
Catalog # | 18460-250 |
Price | $100.00 |
Order / More Info | Nicorandil from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |