MK-571 from CAYMAN CHEMICAL COMPANY

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Product NameMK-571
DescriptionA CysLT1 receptor antagonist (Ki = 2.1 nM in a radioligand binding assay using isolated human lung membranes); inhibits contractions induced by LTD4 or LTE4 in histamine-primed isolated guinea pig trachea (pA2 = 9.4 and 9.1, respectively), but not contractions induced by LTC4 in histamine-primed isolated guinea pig trachea at 190 nM; inhibits LTD4-induced calcium mobilization in COS-7 cells expressing the human CysLT1 receptor at 100 nM; improves tissue damping and elasticity, markers of lung function, and decreases IL-4 and IL-5 levels in BALF in a mouse model of ovalbumin-induced asthma at 5 mg/kg
Size50 mg
Concentrationn/a
Applicationsn/a
Other NamesL-660,711
Gene, Accession, CAS #CAS: 115104-28-4
Catalog #10029-50
Price$533.00
Order / More InfoMK-571 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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