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Product Name | MK-571 |
Description | A CysLT1 receptor antagonist (Ki = 2.1 nM in a radioligand binding assay using isolated human lung membranes); inhibits contractions induced by LTD4 or LTE4 in histamine-primed isolated guinea pig trachea (pA2 = 9.4 and 9.1, respectively), but not contractions induced by LTC4 in histamine-primed isolated guinea pig trachea at 190 nM; inhibits LTD4-induced calcium mobilization in COS-7 cells expressing the human CysLT1 receptor at 100 nM; improves tissue damping and elasticity, markers of lung function, and decreases IL-4 and IL-5 levels in BALF in a mouse model of ovalbumin-induced asthma at 5 mg/kg |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | L-660,711 |
Gene, Accession, CAS # | CAS: 115104-28-4 |
Catalog # | 10029-50 |
Price | $533.00 |
Order / More Info | MK-571 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |