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Product Name | RS 102221 (hydrochloride) |
Description | A 5-HT2C receptor antagonist; binds to 5-HT2C receptors (Ki = 3.8 nM for the recombinant human receptor) and is selective for 5-HT2C receptors over 5-HT2A and 5-HT2B receptors (Kis = 1,122.02 and 812.83 nM, respectively), as well as a panel of additional neurotransmitter receptors and ion channels (Kis = ≥316.23 nM for all); inhibits 5-HT-induced increases in the extracellular media acidification rate of CHO-K1 cells expressing human 5-HT2C receptors (pA2 = 8.1); increases food intake and weight gain in rats at 2 mg/kg; increases the time spent in the light compartment in the light-dark exploration test in mice at 2 mg/kg; reduces prepulse inhibition of the startle reflex in mice at 1 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 185376-97-0 RS102221 5HT HT-2C HT-2-C HT2-C A B CHOK1 CHO-K-1 CHO-K-1 CHOK-1 pA-2 neuro transmitter extra cellular |
Gene, Accession, CAS # | CAS: 187397-18-8 |
Catalog # | 31543-5 |
Price | $169.00 |
Order / More Info | RS 102221 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |