AS-604850 from CAYMAN CHEMICAL COMPANY
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| Product Name | AS-604850 |
| Description | AS-604850 is a selective, ATP-competitive inhibitor of PI3Kγ with IC50 values of 0.25, >20, >20, and 4.5 µM for the human recombinant γ, .delta., β, and α isoforms, respectively.{13338} AS-604850 inhibited MCP-1-mediated monocyte chemotaxis with an IC50 value of 21 µM and reduced RANTES-induced peritoneal neutrophil recruitment in a murine model of leukocyte chemotaxis with an ED50 value of 42.4 mg/kg.{13338} |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | phosphoinositides 3-kinases PI3-kinase PI3-K phosphatidylinositol inflammatory drugs inflammation arthritis rheumatoid peritonitis neutrophils recruitment PtdIns inhibitors inhibits inhibiton PI3K AS604850 AS 604850 |
| Gene, Accession, CAS # | CAS: 648449-76-7 |
| Catalog # | 10010175-10 |
| Price | $195.00 |
| Order / More Info | AS-604850 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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