CP 105,696 from CAYMAN CHEMICAL COMPANY

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Product NameCP 105,696
DescriptionA LTB4 receptor antagonist (IC50 = 8.42 nM for the high-affinity receptor in human neutrophils); inhibits LTB4-induced chemotaxis in isolated human neutrophils (IC50 = 5 nM) and LTB4-induced calcium mobilization in isolated human monocytes (IC50 = 940 nM); reduces arachidonic acid-induced infiltration of neutrophils and eosinophils in guinea pig skin (ED50 = 0.3 mg/kg, p.o.); decreases blood glucose levels in the glucose tolerance test and reduces hepatic steatosis in a mouse model of obesity induced by a high-fat diet; decreases disease severity in a mouse model of EAE (ED50 = 8.6 mg/kg); increases graft survival in a mouse model of allogeneic heart transplantation at 50 mg/kg
Size5 mg
Concentrationn/a
Applicationsn/a
Other Names186912-87-8 CP105696 LTB-4
Gene, Accession, CAS #CAS: 158081-99-3
Catalog #17620-5
Price$95.00
Order / More InfoCP 105,696 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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