VU0119498 from CAYMAN CHEMICAL COMPANY
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| Product Name | VU0119498 |
| Description | An M1, M3, and M5 muscarinic receptor positive allosteric modulator (EC50s = 6.04, 6.38, and 4.08 µM, respectively, in calcium mobilization assays); selective for M1, M3, and M5 mAChRs over M2 and M4 mAChRs in CHO cells expressing the human receptors; enhances ACh-induced insulin secretion in MIN6-K8 pancreatic β-cells at 20 µM; decreases glucose tolerance and increases insulin secretion in mice fed normal chow, as well as in a mouse model of high-fat diet-induced obesity, at 0.5 mg/kg |
| Size | 250 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | VU-0119498 VUo119498 VUo-119498 MIN6K8 M-1 5 Z 57823200 Z57823200 N-Bromobenzylisatin Bromobenzyl) Bromobenzyl)indole Bromobenzyl)indoline dihydro Bromophenyl)methyl]indole |
| Gene, Accession, CAS # | CAS: 79183-37-2 |
| Catalog # | 36132-250 |
| Price | $310.00 |
| Order / More Info | VU0119498 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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