XMD8-92 from CAYMAN CHEMICAL COMPANY
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| Product Name | XMD8-92 |
| Description | A selective ERK5 inhibitor (Kd = 80 nM); less potently inhibits DCAMKL2, TNK1, and Plk4 (Kds = 190, 890, and 600 nM, respectively); blocks ERK5 autophosphorylation, ERK5-mediated phosphorylation of PML, and PML-dependent activation of p21; inhibits bFGF-induced angiogenesis in a Matrigel™ plug assay in mice; reduces tumor growth in a HeLa mouse xenograft model at 50 mg/kg twice per day; binds BRD4 (Kd = 170 nM for BRD4 bromodomain 1) |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | XMD892 XMD-8-92 XMD-892 ERK-5 DCAMKL-2 TNK-1 Plk-4 p-21 AP1 MEK-5 Cdc-37 BRD-4 |
| Gene, Accession, CAS # | CAS: 1234480-50-2 |
| Catalog # | 19173-5 |
| Price | $90.00 |
| Order / More Info | XMD8-92 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY