NSC 228155 from CAYMAN CHEMICAL COMPANY
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| Product Name | NSC 228155 |
| Description | An activator of EGFR and an inhibitor of the interaction between the KID of CREB and the KIX domain of CBP (IC50 = 0.36 µM); increases phosphorylation of EGFR at Tyr1068 in MDA-MB-468 cells (EC50 = 52 µM), as well as phosphorylation of ERK1 and ERK2; induces transactivation of InsR, EphA1, ErbB2, ErbB3, IGF-1R, Mer, and ROR1 in MDA-MB-468 cells at 100 µM; inhibits CREB- and VP16-CREB-mediated transcription in HEK293T cell-based reporter assays (IC50s = 2.09 and 6.14 µM, respectively); inhibits P. aeruginosa ribonucleotide reductase (IC50 = 26 µM) and is active against P. aeruginosa (MIC = 50 µM) |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | KIDKIX NSC228155 Tyr-1068 MB468 MDAMB MDAMB468 ERK-1 2 Ins-R EphA-1 Eph-A1 ErbB-3 B2 B3 Erb IGF1R ROR-1 VP16CREB HEK-293T HEK293-T 293 Pseudomonas |
| Gene, Accession, CAS # | CAS: 113104-25-9 |
| Catalog # | 28856-5 |
| Price | $68.00 |
| Order / More Info | NSC 228155 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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http://www.caymanchem.com
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