CB-096 from CAYMAN CHEMICAL COMPANY

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Product NameCB-096
DescriptionAn inhibitor of RAN translation; selectively binds to r(G4C2)8 (EC50 = 19 µM) over r(G2C4)8 and r(GGCC)10; inhibits RAN translation and the formation of nuclear stress granules in HEK293T cells expressing r(G4C2)66 in an in vitro model of c9ALS/FTD at 25 µM; induces relaxation of rat thoracic aortic rings pre-contracted with norepinephrine (EC50 = 1.81 µM) and decreases systolic arterial pressure in conscious spontaneously hypertensive rats when administered at a dose of 100 mg/kg
Size10 mg
Concentrationn/a
Applicationsn/a
Other NamesAN-353 AN353 CB096 CB-96 CB96 HEK-293T c9ALS c9FTD
Gene, Accession, CAS #CAS: 108883-90-5
Catalog #36407-10
Price$216.00
Order / More InfoCB-096 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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