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Product Name | CB-096 |
Description | An inhibitor of RAN translation; selectively binds to r(G4C2)8 (EC50 = 19 µM) over r(G2C4)8 and r(GGCC)10; inhibits RAN translation and the formation of nuclear stress granules in HEK293T cells expressing r(G4C2)66 in an in vitro model of c9ALS/FTD at 25 µM; induces relaxation of rat thoracic aortic rings pre-contracted with norepinephrine (EC50 = 1.81 µM) and decreases systolic arterial pressure in conscious spontaneously hypertensive rats when administered at a dose of 100 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | AN-353 AN353 CB096 CB-96 CB96 HEK-293T c9ALS c9FTD |
Gene, Accession, CAS # | CAS: 108883-90-5 |
Catalog # | 36407-10 |
Price | $216.00 |
Order / More Info | CB-096 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |