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Product Name | QLT0267 |
Description | An ILK inhibitor (IC50 = 26 nM); greater than 10-fold selective for ILK over Cdk1, -2, and -5, as well as greater than 1,000-fold selective for ILK over CSK, DNA-PK, Pim-1, Akt, PKC, and CK2, at 10 mg/ml; inhibits the growth of NPA187 cells (IC50 = ~3 µM); induces apoptosis in NPA187, DRO, and K4 cancer cell lines; reduces tumor growth in a DRO mouse xenograft model at 100 mg/kg; reduces tumor volume and intratumoral blood vessel mass in a U87MG glioblastoma mouse xenograft model |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 6975-75-3 QLT 0267 Cdk 1 2 5 DNAPK Pim1 NPA 187 |
Gene, Accession, CAS # | CAS: 866409-68-9 |
Catalog # | 34309-10 |
Price | $249 |
Order / More Info | QLT0267 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |