Ivacaftor from CAYMAN CHEMICAL COMPANY
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| Product Name | Ivacaftor |
| Description | A CFTR potentiator; increases the forskolin-induced CFTR-mediated epithelial current in cells expressing the G551D missense mutation by ~4-fold (EC50 = 100 nM); increases chloride secretion in cultured human cystic fibrosis bronchial epithelial cells carrying the G551D mutation on one allele and the common ΔF508 processing mutation on the other allele; binds CFTR directly and leads to CFTR channel opening via an ATP-independent mechanism |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | VX 770 |
| Gene, Accession, CAS # | CAS: 873054-44-5 |
| Catalog # | 15145-10 |
| Price | $245.00 |
| Order / More Info | Ivacaftor from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY