Brevilin A from CAYMAN CHEMICAL COMPANY
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| Product Name | Brevilin A |
| Description | A sesquiterpene lactone with anticancer activity; an inhibitor of STAT3 signaling (IC50 = 10.6 µM in A549R cells); inhibits the tyrosine kinase activity of the JAK1, JAK2, JAK3, and JAK4 JH1 subunit (IC50s = 11.2, 8.4, 10.2, and 11.9 µM, respectively); inhibits proliferation of a variety of cancer cells in a concentration-dependent manner; decreases the mitochondrial membrane potential, induces apoptosis, and increases ROS levels in CT26 cells; induces autophagosome formation in a PI3K-dependent manner; increases intratumor expression of LC3-II and reduces tumor growth in a murine CT26 colon cancer model at 5 mg/kg per day |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 6-O-Angeloylprenolin|Brevelin A |
| Gene, Accession, CAS # | CAS: 16503-32-5 |
| Catalog # | 33993-1 |
| Price | $106.00 |
| Order / More Info | Brevilin A from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY