Prunetin from CAYMAN CHEMICAL COMPANY
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| Product Name | Prunetin |
| Description | An isoflavone with diverse biological activities; an allosteric inhibitor of hamster ALDH2 (IC50 = 0.45 µM); an antagonist of the progesterone receptor at 25 and 50 µM; has estrogenic activity in MVLN cells at 1-50 µM and inhibits proliferation of MCF-7 breast cancer cells at 0.01-50 µM; decreases LPS-induced increases in NO and PGE2 levels, NOS2/iNOS expression, and NF-κB activation in RAW 264.7 macrophages at 50 and 100 µM; prevents LPS-induced increases in serum TNF-α, IL-1β, and IL-6 levels in a mouse model of septic shock at 10 mg/kg; prevents the production of MMP-3 in the knee joint of rats in a model of osteoarthritis following administration of a 50 or 100 µM dose into the knee joint |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 4 Dihydroxy methoxyisoflavone O-Methylgenistein iso-flavone Prunus ALDH-2 MCF7 PGE E NOS-2 i-NOS NFκB RAW264.7 TNFα IL1β IL6 MMP3 macro-phages |
| Gene, Accession, CAS # | CAS: 552-59-0 |
| Catalog # | 29432-25 |
| Price | $379 |
| Order / More Info | Prunetin from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY