DO264 from CAYMAN CHEMICAL COMPANY
Search, find, compare suppliers for DO264 products.
| Edit | |
|---|---|
| Product Name | DO264 |
| Description | An ABHD12 inhibitor (IC50 = 11 nM); inhibits ABHD-dependent hydrolysis of lyso-PS in mouse brain membrane lysates (IC50 = 2.8 nM) and human THP-1 cells; increases levels of CCL3, CCL4, TNF-α, and IL-1β in M1-polarized THP-1 macrophages; increases levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PS, 1-arachidonoyl-2-hydroxy-sn-glycero-3-PS, 1-docosanoyl-2-hydroxy-sn-glycero-3-PS, 1-stearoyl-2-arachidonoyl-sn-glycero-3-PS, and 1-oleoyl-2-arachidonoyl-sn-glycero-3-PS in mouse brain at 30 mg/kg per day for four weeks; increases levels of CCL2, CCL3, and CCL5 in BALF and decreases survival in a mouse model of infection with LCMV clone 13 at 30 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | DO-264 ABHD-12 lyso-phosphatidylserine phosphatidyl-serine lysophosphatidyl lysoPS CCL-3 4 5 2 TNFα IL1β M1polarized THP1 broncho-alveolar clone13 |
| Gene, Accession, CAS # | CAS: 2301866-59-9 |
| Catalog # | 29402-5 |
| Price | $324.00 |
| Order / More Info | DO264 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY