SF2523 from CAYMAN CHEMICAL COMPANY
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| Product Name | SF2523 |
| Description | A dual inhibitor of PI3K and BRD4 (IC50s = 16, and 241 and 1,550 nM for PI3K, and BRD4 bromodomains 1 and 2, respectively); reduces MYCN gene expression and decreases MYCN and cyclin D1 protein levels; inhibits phosphorylation of Akt in SKNBE2 cells; reduces tumor volume and protein levels of MYCN and cyclin D1 in a MYCN-amplified SKNBE2 neuroblastoma xenograft model in mice; reduces tumor growth and the number of colonic lymph node metastases in the murine orthotopic pancreatic Panc02 carcinoma model |
| Size | 500 µg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | SF-2523 BRD-4 2 1 Panc-02 SKNBE-2 BRD1 BRD2 |
| Gene, Accession, CAS # | CAS: 1174428-47-7 |
| Catalog # | 21638-500 |
| Price | $57.00 |
| Order / More Info | SF2523 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY