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Product Name | AUTEN-99 |
Description | An inhibitor of MRMR14/Jumpy; inhibits MTMR14/Jumpy activity in a cell-free assay at 10 and 100 µM; enhances autophagic flux and increases the levels of LC3B-11 in HeLa cells at 1 and 10 µM; increases survival of mouse primary neurons exposed to hydrogen peroxide as a model of oxidative stress at 0.5-5 µM; increases the number of autophagic structures in mouse pancreas, kidney, and liver; induces autophagy in the Drosophila larval fat body and increases the percentage of flies climbing a glass column in a climbing assay in a transgenic model of Parkinson's disease |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Autophagy Enhancer-99 |
Gene, Accession, CAS # | CAS: 1049780-58-6 |
Catalog # | 30047-25 |
Price | $533.00 |
Order / More Info | AUTEN-99 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |