PLX7904 from CAYMAN CHEMICAL COMPANY

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Product NamePLX7904
DescriptionA RAF inhibitor (IC50s = 2.4, 140, and 91 nM for mutant B-RAFV600E, wild-type B-RAF, and C-RAF, respectively); inhibits phosphorylation of ERK in A375 and COLO 829 cells (IC50s = 16 and 18 nM, respectively); does not induce paradoxical pERK activation and proliferation of cancer cell lines (EC50s = >200 µM); inhibits tumor growth in a mouse COLO 205 colon cancer xenograft model ,
Size1 mg
Concentrationn/a
Applicationsn/a
Other NamesPLX-7904 4032 BRAF V600E CRAF A-375 BAY-439006 BAY439006 COLO829 COLO205
Gene, Accession, CAS #CAS: 1393465-84-3
Catalog #20710-1
Price$38
Order / More InfoPLX7904 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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