WYE-687 from CAYMAN CHEMICAL COMPANY
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| Product Name | WYE-687 |
| Description | An mTOR inhibitor (IC50 = 0.007 µM); selective for mTOR over PI3Kα and PI3Kγ (IC50s = 0.81 and 3.11 µM, respectively), as well as a panel of 24 additional kinases (IC50s = >50 µM for all); decreases phosphorylation of the mTORC1 and mTORC2 substrates Akt and S6K1, respectively, in a cell-free assay at 0.2, 1, and 5 µM; decreases proliferation of nine cancer cell lines (IC50s = 0.18-1.25 µM); inhibits survival of HL-60 and U937 leukemia cells; reduces tumor growth in a U937 mouse xenograft model at 5 and 25 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | WAY-687 |
| Gene, Accession, CAS # | CAS: 1062161-90-3 |
| Catalog # | 29977-5 |
| Price | $152.00 |
| Order / More Info | WYE-687 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY