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Product Name | Neurofibrillary Tangle BODIPY (600/710 nm) |
Description | A fluorescent probe for neurofibrillary tangles; binds to tau-K18 aggregates in a cell-free assay (Kd = 16.8 nM) and is 2.17-fold selective for tau-K18 over Aβ42 aggregates; has been used to label NFTs in postmortem hippocampus from patients with Alzheimer's disease; has been used to identify tauopathy in vivo and ex vivo in transgenic human tauP301L-expressing mice with a lower signal occurring in the brain of wild-type mice; ex/em = 570-600/710-774 nm in methylene chloride, THF, methanol, DMSO, and PBS |
Size | 100 µg |
Concentration | n/a |
Applications | Fluorescence |
Other Names | NFT BODIPY (600/710 nm)|?TNIR7-1A |
Gene, Accession, CAS # | CAS: 2301931-35-9 |
Catalog # | 40243-100 |
Price | $149.00 |
Order / More Info | Neurofibrillary Tangle BODIPY (600/710 nm) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |