RN-1734 from CAYMAN CHEMICAL COMPANY
Search, find, compare suppliers for RN-1734 products.
| Edit | |
|---|---|
| Product Name | RN-1734 |
| Description | A TRPV4 antagonist (IC50s = 2.3, 5.9, and 3.2 µM for human, mouse, and rat, respectively), selective for TRPV4 over TRPV1, TRPV3, and TRPM8 (IC50s = >100, >30, and >30 µM, respectively), reduces GSK1016790A-induced increases in IGly from 34.5 to 0.97% in mouse hippocampal neurons in vitro (10 µM); blocks GSK1016790A-induced arteriolar dilation and increases myogenic tone in rat cremaster arterioles ex vivo (30 µM), reduces edema and MAPK signaling induced by traumatic brain injury in rats (1 mg/kg, i.p.), inhibits breakdown of the blood-retinal barrier in streptozotocin-induced diabetic rats (100 µM) |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | RN1734 TRPV -4 1 3 TRPM-8 GSK-1016790A |
| Gene, Accession, CAS # | CAS: 946387-07-1 |
| Catalog # | 24205-5 |
| Price | $61 |
| Order / More Info | RN-1734 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY