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Product Name | Erastin |
Description | A ferroptosis inducer; induces ferroptotic cell death in vitro, an effect that can be blocked by ferroptosis inhibitors; inhibits cystine uptake by the system xc- cystine-glutamate transporter in HT-1080 fibrosarcoma and Calu-1 lung carcinoma cells at 5 µM; inhibits glutamate release via the cystine-glutamate transporter in an enzyme-coupled fluorescence assay (EC50 = 1.2 µM); selectively induces cell death in cells expressing the SV40 small T oncoprotein and oncogenic Ras (IC50s = 1.25-5 µg/ml) |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | oncoprotein oncogene Ras antitumor cancer mitochondrial oxidative injury anti tumor |
Gene, Accession, CAS # | CAS: 571203-78-6 |
Catalog # | 17754-50 |
Price | $849.00 |
Order / More Info | Erastin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |