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Product Name | Rotenone |
Description | An inhibitor of mitochondrial complex I; inhibits NADH/DB oxidoreductase and NADH oxidase (IC50s = 28.8 and 5.1 nM, respectively); increases ROS production in the mitochondria of substantia nigra pars compacta neurons; induces Parkinson-like neuropathology and behavior in rodents; reduces tyrosine hydroxylase levels in the posterior striatum and prefrontal cortex, induces catalepsy, and decreases spontaneous locomotion and exploration in the open field test in rats at 1.5 and 2.5 mg/kg per day for two months; commonly used as a model of Parkinson's in rodents |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Nicouline|NSC 26258|NSC 8505|Tubatoxin |
Gene, Accession, CAS # | CAS: 83-79-4 |
Catalog # | 13995-100 |
Price | $129 |
Order / More Info | Rotenone from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |