CAY10748 from CAYMAN CHEMICAL COMPANY
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| Product Name | CAY10748 |
| Description | A STING agonist (IC50 = 0.3794 µM in a competition binding assay); activates STING in STING-expressing, but not STING knockout, THP-1 cells (EC50s = 0.287 and >100 µM, respectively, in a reporter assay); activates the STING-TBK1-IRF3 signaling pathway; increases the secretion of IFN-β and the levels of CXCL10 and IL-6 in PBMCs at 10 µM; reduces tumor growth in a CT26 murine colon cancer model at 0.15, but not 1.5, mg/kg |
| Size | 500 µg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CAY 10748 THP1 TBK 1 STINGTBK1IRF3 STING TBK1IRF3 STINGTBK1 IRF3 |
| Gene, Accession, CAS # | CAS: 2412902-55-5 |
| Catalog # | 30022-500 |
| Price | $49.00 |
| Order / More Info | CAY10748 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY