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Product Name | ML-290 |
Description | An RXFP1 agonist (EC50 = 0.094 µM for the human receptor in a cAMP production assay); selective for RXFP1 over RXFP2 (EC50 = 1.5 µM); induces expression of VEGF in THP-1 cells expressing human RXFP1 at 250 nM; stimulates cAMP release from HEK293 cells expressing the human, macaque, pig, or rabbit receptors, but not the guinea pig or mouse receptors; increases the expression of MMP1 and PPARGC1A and decreases COL1A1 expression in primary human hepatic stellate cells at 5 µM; reduces carbon tetrachloride-induced liver fibrosis in transgenic mice expressing human RXFP1 at 37 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | RXFP1 Agonist 8?? |
Gene, Accession, CAS # | CAS: 1482500-76-4 |
Catalog # | 21134-1 |
Price | $38.00 |
Order / More Info | ML-290 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |