KMN-80 from CAYMAN CHEMICAL COMPANY
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| Product Name | KMN-80 |
| Description | A selective, potent agonist of EP4 with an IC50 value of 3 nM (versus 1.4 µM for EP3 and > 10 µM for all other prostanoid receptors) and an EC50 value of 0.19 nM in functional assays; induces the differentiation of bone marrow stem cells from both young and aged rats into osteoblasts in vitro (EC50s = 20 and 153 nM, respectively); repairs calvarial defects in an in vivo rat craniomaxillofacial reconstruction model and promotes bone formation in a rat incisor tooth socket model |
| Size | 500 µg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | EP4 receptors agonists prostaglandins E2 PGE2 E1 PGE1 bones formations resorption marrow stem cells differentiation L-902,688 calvarial defect BMP2 bone regeneration bone matrix KMNs 80 KMN80 pyrrolidinone derivatives |
| Gene, Accession, CAS # | CAS: 1628759-75-0 |
| Catalog # | 15435-500 |
| Price | $107.00 |
| Order / More Info | KMN-80 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY