Zopolrestat from CAYMAN CHEMICAL COMPANY
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| Product Name | Zopolrestat |
| Description | A potent aldose reductase inhibitor (IC50s = 1.9 and 41 nM for the human placenta and rat lens enzymes, respectively); inhibits sorbitol accumulation in human and rat erythrocytes (IC50s = 370 and 220 nM, respectively); inhibits ethanol-induced aldose reductase activity and lipid accumulation in HepG2 cells at 50 µM; reduces sciatic nerve, retina, and lens accumulation of sorbitol in a rat model of STZ-induced diabetes at 50 mg/kg; reduces protein excretion and maintains lens transparency and myo-inositol content in rats with STZ-induced diabetes at 100 mg/kg; inhibits GLOI (Ki = 18 µM) |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Hep G2 myoinositol GLO I CP 73850 CP73850 |
| Gene, Accession, CAS # | CAS: 110703-94-1 |
| Catalog # | 29185-10 |
| Price | $214.00 |
| Order / More Info | Zopolrestat from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY