Edit |   |
---|---|
Product Name | IC87201 |
Description | An inhibitor of the nNOS-PSD-95 protein-protein interaction; inhibits the binding of PSD-95 to nNOS (IC50 = 31 µM); inhibits NMDA-induced cGMP production in primary rat hippocampal neurons (IC50 = 2.7 µM); reduces MPP+-induced production of ROS, cytochrome c release, and apoptosis in primary rat cortical neurons at 10 µM; decreases thermal hyperalgesia in mice (ED50 = 0.1 mg/kg), as well as mechanical allodynia in a rat model of CCI-induced neuropathic pain; reduces immobility time in the forced swim and tail suspension tests in mice at 1 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | IC 87201 n NOS PSD95 |
Gene, Accession, CAS # | CAS: 866927-10-8 |
Catalog # | 32973-10 |
Price | $155.00 |
Order / More Info | IC87201 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |