KD 025 from CAYMAN CHEMICAL COMPANY
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| Product Name | KD 025 |
| Description | A ROCK2 inhibitor (IC50 = 0.105 µM); selective for ROCK2 over ROCK1 (IC50 = 24 µM); decreases the expression of CTGF and induces remodeling of the actin cytoskeleton in isolated human ileal fibrotic smooth muscle cells at 10 µM; inhibits heat-killed C. albicans- or S. epidermidis-induced production of IL-17 in isolated human PBMCs at 1.25-10 µM; reduces infarct volume in a mouse model of cerebral ischemia induced by transient MCAO at 100 and 200 mg/kg; decreases disease severity in a mouse model of sclerodermatous chronic GVHD at 150 mg/kg |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Belumosudil|SLx-2119 |
| Gene, Accession, CAS # | CAS: 911417-87-3 |
| Catalog # | 17055-25 |
| Price | $140.00 |
| Order / More Info | KD 025 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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