MX1013 from CAYMAN CHEMICAL COMPANY
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| Product Name | MX1013 |
| Description | A dipeptide pan-caspase inhibitor; inhibits caspase-1 (IC50 = 20 nM), caspase-3 (IC50 = 30 nM), and caspase-6, -7, -8, and -9 (IC50s = 5-18 nM); selective for caspases over calpain I, cathepsin B, cathepsin D, renin, thrombin, and Factor Xa (IC50s = >10 µM); inhibits anti-Fas antibody-induced caspase-3 processing and PARP cleavage in Jurkat cells at 0.05 µM; increases survival in a mouse model of anti-Fas antibody-induced liver failure at ≥0.25 mg/kg; reduces infarct size in rat models of acute myocardial infarction-reperfusion or transient focal brain ischemia-reperfusion injury intravenously as a 20 mg/kg bolus dose followed by a 5 mg/kg per hour infusion |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Z-Val-Asp-Fluoromethyl Ketone|Z-VD-FMK |
| Gene, Accession, CAS # | CAS: 582316-00-5 |
| Catalog # | 27904-25 |
| Price | $268.00 |
| Order / More Info | MX1013 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY