BFH772 from CAYMAN CHEMICAL COMPANY
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| Product Name | BFH772 |
| Description | An inhibitor of VEGFR2 (IC50 = 0.0027 µM for the human receptor); selective for human VEGFR2 over mouse VEGFR2 and human VEGFR1 and VEGFR3 (IC50s = 1.5, 1.7, and 1.1 µM, respectively), as well as 40-fold selective over B-RAF, RET, and Tie2; inhibits VEGF-induced proliferation of HUVECs (IC50 = <0.01 nM); inhibits VEGF-induced increases in tissue weight and Tie2 levels in an angiogenesis chamber implant model in mice at 1 and 3 mg/kg per day; inhibits primary tumor and metastasis growth in a B16 melanoma mouse model at 3 mg/kg per day |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | BFH-772 VEGFR-1 2 3 BRAF Tie-2 B-16 |
| Gene, Accession, CAS # | CAS: 890128-81-1 |
| Catalog # | 21386-10 |
| Price | $292.00 |
| Order / More Info | BFH772 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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