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Product Name | ARUK3001185 |
Description | An inhibitor of NOTUM (IC50 = 6.7 nM); selective for NOTUM over a panel of 39 serine hydrolases and 485 kinases, including CK1 and GSK3, at 10 µM and a panel of 47 receptors, ion channels, transporters, and enzymes at 30 µM, but does inhibit 5-HT3A, α4β2 subunit-containing nAChRs, and MAO-A (IC50s = 4.5, 10, and 28 µM, respectively); prevents NOTUM-induced decreases in Wnt3a signaling in a cell-based reporter assay (EC50 = 110 nM) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-Phenyl-1H-1,2,3-triazole 1 |
Gene, Accession, CAS # | CAS: 2411969-39-4 |
Catalog # | 37113-10 |
Price | $376.00 |
Order / More Info | ARUK3001185 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |