Urapidil (hydrochloride) from CAYMAN CHEMICAL COMPANY

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Product NameUrapidil (hydrochloride)
DescriptionAn α1-AR antagonist and partial 5-HT1A agonist; selectively binds to α1- over α2-ARs (IC50s = 0.74 and 42 µM, respectively) and to 5-HT1A over 5-HT1B and 5-HT2 receptors (IC50s = 0.4, 20.4, and >10 µM, respectively) in rat cortex; inhibits forskolin-induced cAMP accumulation in calf hippocampus as a functional model for 5-HT1A receptors (EC50 = 390 nM); inhibits the isoproterenol-induced positive chronotroptic response in isolated rat atria (pA2 = 6.05); lowers MAP in anesthetized cats at 1 µmol/kg, i.v.
Size500 mg
Concentrationn/a
Applicationsn/a
Other Names34661-75-1 α-1 α1AR 5HT 1-A 1-B HT-1A HT-2 α-2 α2AR β-1 β1AR pA-2
Gene, Accession, CAS #CAS: 64887-14-5
Catalog #29004-500
Price$122.00
Order / More InfoUrapidil (hydrochloride) from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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