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Product Name | Eact |
Description | An ANO1 channel activator; increases chloride currents in FRT cells expressing human ANO1 (EC50 = 3 µM); selective for ANO1 over CFTR and ENaCs in FRT cells at 10 µM; increases the rate of submucosal gland fluid secretion in human bronchi isolated from patients with cystic fibrosis and healthy individuals at 20 µM; increases production of mitochondrial ROS, reduces the mitochondrial membrane potential, and induces apoptosis in RLMVECs; reduces total cell counts in pulmonary artery endothelial cell populations isolated from patients with IPAH; activates TRPV1 in HEK293T cells expressing the mouse receptor (EC50 = 11.6 µM); induces scratching and licking behaviors in wild-type, but not Trpv1-/-, mice |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ANO 1 CF TRPV 1 HEK 293T 293 T HEK293 Trpv |
Gene, Accession, CAS # | CAS: 461000-66-8 |
Catalog # | 29791-10 |
Price | $213.00 |
Order / More Info | Eact from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |