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Product Name | DMHCA |
Description | An LXR agonist; activates LXRα and LXRβ in CV-1 cells expressing the human receptors in reporter assays (EC50 = 2 µM for both); inhibits DHCR24 (IC50 = 0.7 nM); does not induce steatosis or increase liver triglyceride levels compared with T0901317 in mice at 80 mg/kg; reduces the size of atherosclerotic lesions in ApoE-/- mice fed a Western diet; decreases proteinuria and hepatic cholesterol levels in a mouse model of streptozotocin-induced diabetic nephropathy |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Dimethyl-HCA|N,N-Dimethyl-3β-hydroxycholenamide |
Gene, Accession, CAS # | CAS: 79066-03-8 |
Catalog # | 37712-25 |
Price | $383.00 |
Order / More Info | DMHCA from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |