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Product Name | Questiomycin A |
Description | A phenoxazine and chromophore with antibacterial and anticancer activities; active against M. scrofulaceum, M. marinum, and M. intracellulare (MICs = 2.8, 11.3, and 5.6 µg/ml, respectively) but not M. tuberculosis, M. smegmatis, M. kansasii, or M. fortuitum (MICs = >45 µg/ml); cytotoxic to a variety of cancer cells, including MCF-7, A549, MIA PaCa-2, and LoVo-1 cells (IC50s = 1.67, 5.48, 7.16, and 20.03 µM, respectively) as well as HUVECs but not HELs (IC50s = 16.06 and >50 µM, respectively); prevents lung metastasis in a B16 mouse melanoma model of metastasis at 0.5 mg/kg when administered simultaneously with B16 cells or every three days; has been used as a readout in the study of catalytic oxidation of 2-aminophenol by various metal-containing complexes |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | anti bacterial cancer Mycobacterium Escherichia Pseudomonas Salmonella Staphylococcus Listeria MCF7 A 549 MiaPaCa2 PaCa2 MiaPaCa LoVo1 B 16 Phx-3 Phx3 2-amino-3-Phenoxazone 2-Aminophenoxazinone |
Gene, Accession, CAS # | CAS: 1916-59-2 |
Catalog # | 27623-5 |
Price | $319 |
Order / More Info | Questiomycin A from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |