Ki20227 from CAYMAN CHEMICAL COMPANY
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| Product Name | Ki20227 |
| Description | A c-Fms kinase inhibitor (IC50 = 2 nM); inhibits CSF1-dependent c-Fms phosphorylation in a dose-dependent manner in RAW264.7 cells; reduces CSF1-dependent growth of M-NFS-60 cells (IC50 = 14 nM); suppresses development of TRAP-positive osteoclast-like cells from murine bone marrow (IC50 = 40 nM); decreases the number and area of osteolytic lesions on femurs and tibiae in a murine A375 subcutaneous xenograft model; reduces TNF-α infiltration and osteolytic bone destruction in a CIA mouse model, |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Ki MNFS60 MNFS NFS60 CSF-1 20227 cFMS |
| Gene, Accession, CAS # | CAS: 623142-96-1 |
| Catalog # | 22258-10 |
| Price | $196.00 |
| Order / More Info | Ki20227 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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http://www.caymanchem.com
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