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Product Name | α-Conotoxin AuIB (trifluoroacetate salt) |
Description | A conotoxin and an antagonist of α3β4 subunit-containing nAChRs (IC50 = 0.75 µM); >100-fold selective for α3β4 subunit-containing nAChRs over those containing α2β2, α2β4, α3β2, α4β2, α4β4, or α1β1γδ subunits but does inhibit homomeric α7 nAChRs by 34% at 3 µM; reduces mechanical allodynia in a rat model of neuropathic pain induced by partial sciatic nerve ligation at 0.2 and 2 nmol, intrathecally; reverses somatic signs of withdrawal in a mouse model of morphine withdrawal at 1.75 and 3.5 pmol, i.c.v. |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | GCCSYPPCFATNPDC |
Gene, Accession, CAS # | n/a |
Catalog # | 33795-500 |
Price | $425.00 |
Order / More Info | α-Conotoxin AuIB (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |