SR 1903 from CAYMAN CHEMICAL COMPANY
Search, find, compare suppliers for SR 1903 products.
| Edit | |
|---|---|
| Product Name | SR 1903 |
| Description | A modulator of RORγ and LXR receptors; an inverse agonist of RORγ (IC50 = ~100 nM) and an agonist of LXR; binds to PPARγ (IC50 = 209 nM) but does not activate it; inhibits LPS-induced expression of TREM-1 in RAW 264.7 cells at 10 µM; inhibits LPS-induced expression of the LXR target genes IL-6 and IL-33 and increases expression of ABCG1, FASN, and SCD-1 in RAW 264.7 cells; reduces severity score in a mouse model of collagen-induced arthritis at 20 mg/kg twice per day; reduces blood glucose levels in a glucose tolerance test, serum levels of total cholesterol and LDL, body weight, and fat mass in a mouse model of high-fat diet-induced obesity |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | SR1903 ROR PPAR lipopolysaccharide TREM1 RAW264.7 IL6 IL33 ABCG SCD1 low density lipoprotein |
| Gene, Accession, CAS # | CAS: 1414248-06-8 |
| Catalog # | 28253-10 |
| Price | $249.00 |
| Order / More Info | SR 1903 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY