Capadenoson from CAYMAN CHEMICAL COMPANY

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Product NameCapadenoson
DescriptionAn orally bioavailable, non-nucleoside partial adenosine receptor agonist; binds selectively to human A1 and A2B (EC50s = 0.66 and 1.1 nM, respectively) over A2A and A3 receptors (EC50s = 1,413 and 240 nM, respectively) expressed in CHO cells; decreases electrical field-stimulated norepinephrine release from isolated perfused hearts from SHR but not from control rats at 0.6 µM; protects against stress-induced increases in heart rate in SHR but not control rats at 0.15 mg/kg for 5 days prior to stress induction; decreases cardiac infarct size from 28.7 to 22% in a LAD-induced ischemia mouse model at 0.1 mg/kg; increases LVEF in a microembolization-induced heart failure dog model at 7.5 mg twice daily
Size10 mg
Concentrationn/a
Applicationsn/a
Other NamesBAY 68-4986
Gene, Accession, CAS #CAS: 544417-40-5
Catalog #28422-10
Price$380.00
Order / More InfoCapadenoson from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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